engineered-mspa-protein-nanopore">Single Molecule DNA detection with an engineered MspA protein nanopore

Single molecule DNA detection

Summary

We engineered the nanopore MspA and demonstrated that this enables DNA to move through it. This groundbreaking research laid the foundation for nanopore-based DNA sequencing technology.

Authors

T. Butler, M. Pavlenok, I.M. Derrington, M. Niederweis, and J. Gundlach

Publication

Published in PNAS

DOI: 10.1073/pnas.0807514106

Nanopore tweezers show fractional-nucleotide translocation
Increasing the accuracy of nanopore DNA sequencing
Nanopore DNA sequencing with MspA
Butler, T., Pavlenok, M., Derrington, I.M., Niederweis, M., Gundlach, J. (2008). Single Molecule DNA detection with an engineered MspA protein nanopore. PNAS. doi: 10.1073/pnas.0807514106

15:{"name":"Ian Derrington","title":"Principal Data Scientist","image":"/images/authors/i_logo.png"} 17:["nanopore","MspA","DNA detection","single-molecule","PNAS","biotechnology"] 18:{"facebook":"Breakthrough in DNA detection! Our team engineered the MspA protein nanopore to enable DNA movement through it, laying the foundation for revolutionary sequencing technology.","linkedin":"Excited to share our groundbreaking research published in PNAS! We've successfully engineered the MspA protein nanopore to enable DNA translocation, a crucial step towards nanopore-based DNA sequencing technology. This work opens new possibilities for g

Summary

Authors

Publication

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